Anita K. McElroy, MD, PhD
- Associate Professor, Department of Pediatrics
- Center for Vaccine Research
Education & Training
- MD, George Washington University, 2007
- PhD in Biology, University of California San Diego, 2000
- BS in Microbiology, University of Maryland, 1996
Research Interest Summary
Research Interests
We study the pathogenesis and immunity of emerging viruses with a focus on negative sense RNA viruses of zoonotic potential. To do this we use cell culture systems, animal models and primary human derived specimens. We also use molecular virology to create recombinant viruses to understand how viruses cause disease and perform various immunologic assays to understand how hosts prevent or mitigate disease.
Publications
Mueller Brown K, Barbeau DJ, Xu L, Bird BH, McElroy AK. Humoral immunity is sufficient to protect mice against Rift Valley fever encephalitis following percutaneous exposure. NPJ Vaccines. 2025 Jul 2;10(1):141. doi: 10.1038/s41541-025-01200-2. PubMed PMID: 40603312; PubMed Central PMCID: PMC12222817.
Doyle JD, Barbeau DJ, Cartwright HN, McElroy AK. Immune correlates of protection following Rift Valley fever virus vaccination. NPJ Vaccines. 2022 Oct 28;7(1):129. doi: 10.1038/s41541-022-00551-4. PubMed PMID: 36307416; PubMed Central PMCID: PMC9616434.
Xu L, Paine AC, Barbeau DJ, Alencastro F, Duncan AW, McElroy AK. Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations. J Virol. 2023 Sep 28;97(9):e0085323. doi: 10.1128/jvi.00853-23. Epub 2023 Sep 11. PubMed PMID: 37695055; PubMed Central PMCID: PMC10537571.
Cartwright HN, Barbeau DJ, Doyle JD, Klein E, Heise MT, Ferris MT, McElroy AK. Genetic diversity of collaborative cross mice enables identification of novel rift valley fever virus encephalitis model. PLoS Pathog. 2022 Jul;18(7):e1010649. doi: 10.1371/journal.ppat.1010649. eCollection 2022 Jul. PubMed PMID: 35834486; PubMed Central PMCID: PMC9282606.