Brian T. Campfield, MD
- Assistant Professor, Department of Pediatrics
- Member, Graduate Program in Microbiology and Immunology (PMI)
Education & Training
- MD, University of Pittsburgh, 2006
- BA in Biology, University of Virginia, 2002
Research Interests
Brian Campfield, MD, is an Assistant Professor of Pediatrics at the University of Pittsburgh School of Medicine, within the Department of Pediatrics and Division of Infectious Diseases. After completing his undergraduate degree at the University of Virginia, he received his medical degree from the University of Pittsburgh School of Medicine in 2006. He then completed a pediatric residency in 2009 and pediatric infectious diseases fellowship in 2012 at Children's Hospital of Pittsburgh of UPMC. He then joined the faculty of the University of Pittsburgh School of Medicine with a clinical practice in pediatric infectious diseases and a research focus on novel mechanisms of inflammation and host-pathogen interaction.
His NIH-supported research program centers on discovery and characterization of novel host immune factors, including Follistatin-like protein 1 (FSTL-1), in mediating inflammation and immunity with a focus on lung disease. The central movement of the Campfield lab is translational discovery to harness host immune responses in order to treat life-threatening and drug-resistant infections. Dr. Campfield continues to teach and serve as a research mentor in the University of Pittsburgh School of Medicine, as well as a faculty advisor for medical students, residents, and fellows in the Department of Pediatrics.
Publications
Henkel M, Partyka J, Gregory AD, Forno E, Cho MH, Eddens T, Tout AR, Salamacha N, Horne W, Rao KS, Wu Y, Alcorn JF, Kostka D, Hirsch R, Celedón JC, Kolls JK and Campfield BT*. 2019. Follistatin-like 1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. Am J Respir Crit Care Med. doi: 10.1164/rccm.201905-1973OC. [Epub ahead of print]
Campfield BT*, Eddens T, Henkel M, Majewski M, Horne W, Chaly Y, Gaffen SL, Hirsch R and Kolls JK. 2017. Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells. Immunol Cell Biol. 95: 656-665.
Chen K, Campfield BT, Wenzel SE, McAleer JP, Kreindler JL, Kurland G, Gopal R, Wang T, Chen W, Eddens T, Quinn K, Myerburg MM, Horne WT, Lora JM, Albrecht BK, Pilewski JM and Kolls JK. 2016. Anti-inflammatory Effects of Bromodomain and Extraterminal Domain Inhibition in Cystic Fribrosis Lung Inflammation. JCI Insight. 1: pii: e87168.
Eddens T, Campfield BT, Serody K, Manni ML, Horne W, Elsegeiny W, McHugh KJ, Pociask D, Chen K, Zheng M, Alcorn JF, Wenzel S and Kolls JK. 2016. A Novel CD4+ T-cell Dependent Murine Model of Pneumocystis Driven Asthma-like Pathology. Am J Respir Crit Care Med. 194: 807-820.
Campfield BT, Nolder CL, Davis A, Bushnell D, Marinov A, Hirsch R and Nowalk AJ. 2014. Follistatin-like Protein 1 is a Critical Mediator of Experimental Lyme Arthritis and the Humoral Response to Borrelia burgdorferi Infection. Microb Pathog. 73: 70-79.