Angus Thomson, PhD, DSc

  • Distinguished Professor, Department of Surgery
  • Distinguished Professor, Department of Immunology
  • Professor, Clinical and Translational Science

Education & Training

  • DSc in Medicine, University of Birmingham (UK)
  • DSc, University of Aberdeen (UK)
  • PhD in Immunology, University of Aberdeen (UK)
  • MSc in Immunology, University of Birmingham (UK)
  • BSc (Hons), University of Aberdeen (UK)

Research Interests

  • Regulation of the immune response and design of immunosuppressive therapy; mechanism of action of immune suppressants; immune mechanisms in transplant rejection and autoimmune disease. 
  • Liver transplantation tolerance
  • Cellular immunology, molecular biology and genetic engineering of dendritic cells with special regard to their tolerogenic properties.
  • The roles of cytokines and adhesion molecules in inflammation and immunity. 


Rosborough BR, Raich-Regue D, Matta BM, Lee K, Gan B, Depinho RA, Hackstein H, Boothby M, Turnquist HR and Thomson AW. 2013. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1 and regulatory T cell induction. Blood Epub ahead of print.

Matta BM, Raimondi G, Rosborough BR, Sumpter TL and Thomson AW. 2012. IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells. J. Immunol. 188:5227-5237.

Thomson AW, Turnquist HR and Raimondi G. 2009. Immunoregulatory functions of mTOR inhibition. Nat Rev Immunol 9:324-337.

Turnquist HR, Sumpter TL, Tsung A, Zahorchak AF, Nakao A, Nau GJ, Liew FY, Geller DA and Thomson AW. 2008. IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. J. Immunol. 181:62-72.

Sumpter TL, Packiam V, Turnquist HR, Castellaneta A, Yoshida O and Thomson AW. 2011. DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability. J. Immunol. 186:1970-1980.

Raimondi G, Sumpter TL, Matta BM, Pillai M, Corbitt N, Vodovotz Y, Wang Z and  Thomson AW. 2010. Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients. J. Immunol. 184:624-636.

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