Douglas K. Fischer, PhD

  • Postdoctoral Associate

Why did you choose the University of Pittsburgh?

The University of Pittsburgh has one of the strongest biomedical research programs in the country, and ranks highly in NIH funding. Pitt has a long history of innovations and breakthroughs in the biomedical sciences and is home to numerous noteworthy researchers. The cross-disciplinary and collaborative environment offers unique and exciting opportunities for work and education. All of this in a city voted one of the most livable in the country.

Following his dissertation defense, Dr. Fischer accepted a position as a postdoctoral associate in the lab of his mentor, Dr. Zandrea Ambrose.

Doctoral Dissertation

Examination of the Role of HIV-1 Capsid Sequence on Virus Infectivity, Host Protein Interactions, and Capsid Uncoating

Education & Training

  • PhD in Microbiology and Immunology, University of Pittsburgh, 2019
  • MS in Computer Science, James Madison University, 2001
  • BA in Physics, Bridgewater College, 1995

Research Interests

Host/Pathogen Interactions; Emerging Infectious Diseases; Biosecurity; Astrobiology; Synthetic Biology and Extremophiles; Complex Adaptive Systems


Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P. 2018. Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid. J Virol. Jun 13;92(13)

Hendricks MR, Lashua LP, Fischer DK, Flitter BA, Eichinger KM, Durbin JE, Sarkar SN, Coyne CB, Empey KM and Bomberger JM. 2016. Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. Proc Natl Acad Sci USA. 113: 1642-1647.

Turner MS, Isse K, Fischer DK, Turnquist HR and Morel PA. 2014. Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes. Diabetologia. 57: 1428-1436.